Korean researchers have screened 48 FDA-approved drugs against SARS-CoV-2, and found that two, that are already FDA-approved for other illnesses, seem promising. The FDA approval for other uses would greatly reduce the time needed to gain FDA approval of use in COVID-19. The research is published in Antimicrobial Agents and Chemotherapy, a journal of theContinue reading “Two drugs show promise against COVID-19”
Category Archives: Health
Drug that keeps surface receptors on cancer cells makes them more visible to immune cells
A drug that is already clinically available for the treatment of nausea and psychosis, called prochlorperazine (PCZ), inhibits the internalization of receptors on the surface of tumor cells, thereby increasing the ability of anticancer antibodies to bind to the receptors and mount more effective immune responses. PCZ enhanced the ability of anticancer antibodies to reduceContinue reading “Drug that keeps surface receptors on cancer cells makes them more visible to immune cells”
Drug meant for Ebola may also work against coronaviruses
“Even if you know a drug works, it can be a red flag if you don’t know how it works,” said virologist Matthias Götte. “It is reassuring if you know exactly how it works against the target. “We know the drug works against different coronaviruses, like MERS and SARS, and we know the novel coronavirusContinue reading “Drug meant for Ebola may also work against coronaviruses”
Artificial intelligence yields new antibiotic
The computer model, which can screen more than a hundred million chemical compounds in a matter of days, is designed to pick out potential antibiotics that kill bacteria using different mechanisms than those of existing drugs. “We wanted to develop a platform that would allow us to harness the power of artificial intelligence to usherContinue reading “Artificial intelligence yields new antibiotic”
Modeling study estimates spread of 2019 novel coronavirus
Senior author Professor Gabriel Leung from the University of Hong Kong highlights: “Not everyone who is infected with 2019-nCoV would require or seek medical attention. During the urgent demands of a rapidly expanding epidemic of a completely new virus, especially when system capacity is getting overwhelmed, some of those infected may be undercounted in theContinue reading “Modeling study estimates spread of 2019 novel coronavirus”
How is Chemoinformatics Used in Drug Discovery?
Chemoinformatics is a relatively new principle of chemistry and is based upon the processing of data concerning chemical and molecular structures through the use of computational analysis. The analysis of these data allows the relationship between chemical structure, chemical properties, and molecular activity to be studied. It is an in silico technique, which means itContinue reading “How is Chemoinformatics Used in Drug Discovery?”
Webinar on Pharmaceutical Chemistry 